Evaluation of the optic nerve head and peripapillary retinal nerve fiber layer thickness in patients receiving Electro-Convulsive Therapy
DOI:
https://doi.org/10.15419/bmrat.v4i12.399Keywords:
Electroconvulsive therapy, Optic nerve, Optical coherence tomography, Peripapillary, Retinal nerve fiber layerAbstract
Background: Electroconvulsive therapy (ECT) is a method commonly used in the treatment of psychiatric disorders. As ocular side effects from OCT are less studied and discussed, the aim of this study was to evaluate the profile of the peripapillary retinal nerve fiber layer thickness in patients receiving ECT.
Method: This study was performed on 30 patients who had indication for ECT. After recording demographic data, retinal nerve fiber layer thickness was measured by using spectral domain optical coherence tomography (Heidelberg Engineering, Heidelberg, Germany) of optic nerve head and peripapillary retinal nerve fiber layer.
Results: Our results showed that for most of the studied variables, the normal range was observed in less than 85% of patients receiving ECT. Variables which were outside the normal range were: cup disk (C/D) ratio (right and left eyes were 50% and 46.7%, respectively), vertical C/D ratio (right and left eyes were 53.3% and 46.7%, respectively), and cup volume (right and left eyes were 53.3% and 33.3%, respectively).
Conclusion: This study showed that a high percentage of patients receiving ECT had changes in the optic nerve head while intra-ocular pressure in these patients was normal. It is warranted for examiners to pay attention to diagnosis of normal tension glaucoma in patients receiving ECT.
References
Asl, A.N., Khoshvaghti, A., Najafi, A., Shahraki, K., and Molayi, S. (2014). Evaluation of the intraocular pressure changes after flight with warplanes. Int J Curr res Aca Rev 2014; 2: 222 225.
Boroojeny, S. B., Tabatabai, N. H., Babakhani, B., Babakhani, S., & Moody, Z. (2012). The effect of electroconvulsive therapy using propofol and succinylcholine on the intraocular pressure. Middle East Journal of Anaesthesiology, 21(5), 713–717. PMID:23265035
Dols, A., & Stek, M. L. (2009). [Electroconvulsion therapy]. Nederlands Tijdschrift voor Geneeskunde, 153, A588. PMID:19900318
Edwards, R. M., Stoudemire, A., Vela, M. A., & Morris, R. (1990). Intraocular Pressure Changes in Nonglaucomatous Patients Undergoing Electroconvulsive Therapy. Convulsive Therapy, 6(3), 209–213. PMID:11941069
Good, M. S., Dolenc, T. J., & Rasmussen, K. G. (2004). Electroconvulsive therapy in a patient with glaucoma. The Journal of ECT, 20(1), 48–49. https://doi.org/10.1097/00124509-200403000-00011 PMID:15087998
Lashkari, M. H., Shahraki, K., Najafi, A., Shirzadi, K., Molaei, S., & Shahraki, K. (2014). Evaluation of the optic nerve head and peripapillary retinal nerve fiber layer changes in warplanes pilots. Int J Curr Res Aca Rev, 2(8), 217–221.
Shirzadi, K., Amirdehi, A. R., Makateb, A., Shahraki, K., & Khosravifard, K. (2015). Studying the effect of tropicamide various concentrations on routine dilation of the pupil. Biomedical & Pharmacology Journal, 8(2), 885–889. https://doi.org/10.13005/bpj/839
Khalid, N., Atkins, M., Tredget, J., Giles, M., Champney-Smith, K., & Kirov, G. (2008). The effectiveness of electroconvulsive therapy in treatment-resistant depression: A naturalistic study. The Journal of ECT, 24(2), 141–145. https://doi.org/10.1097/YCT.0b013e318157ac58 PMID:18580559
Mabuchi, F., Yoshimura, K., Kashiwagi, K., Shioe, K., Yamagata, Z., Kanba, S., . . . Tsukahara, S. (2008). High prevalence of anxiety and depression in patients with primary open-angle glaucoma. Journal of Glaucoma, 17(7), 552–557. https://doi.org/10.1097/IJG.0b013e31816299d4 PMID:18854732
Mowla, A., Houshmand, F., & Pani, A. (2013). A Comparison of the practice of Electro convulsive therapy (ECT) for psychiatry patient in department of psychiatry,Fatemeh Zahra hospital, Bushehr, Iran 2008-2009. Iran South Med J, 16(3), 260–267.
O'CONNELL, R.A. (1982). A review of the use of electroconvulsive therapy. Psychiatric Services 33, 469-473.
Pompili, M., Dominici, G., Giordano, G., Longo, L., Serafini, G., Lester, D., . . . Girardi, P. (2014). Electroconvulsive treatment during pregnancy: A systematic review. Expert Review of Neurotherapeutics, 14(12), 1377–1390. https://doi.org/10.1586/14737175.2014.972373 PMID:25346216
Read, J., & Bentall, R. (2010). The effectiveness of electroconvulsive therapy: A literature review. Epidemiologia e Psichiatria Sociale, 19(4), 333–347. https://doi.org/10.1017/S1121189X00000671 PMID:21322506
Saad, D. A., Black, J. L., III, Krahn, L. E., & Rummans, T. A. (2000). ECT post eye surgery: Two cases and a review of the literature. The Journal of ECT, 16(4), 409–414. https://doi.org/10.1097/00124509-200012000-00011 PMID:11314879
Sienaert, P. A., & Vanholst, C. (2013). Electroconvulsive therapy after eye surgery. The Journal of ECT, 29(2), 139–141. https://doi.org/10.1097/YCT.0b013e318279c1ba PMID:23303425
UK ECT Review Group. (2003). Efficacy and safety of electroconvulsive therapy in depressive disorders: A systematic review and meta-analysis. Lancet, 361(9360), 799–808. https://doi.org/10.1016/S0140-6736(03)12705-5 PMID:12642045
Yıldız, N., Uçar, D., Hepokur, M., Baltu, F., Guliyev, E., and Emül, H. (2016). The alteration of retinal nerve fiber layer thickness after ECT sessions. European Neuropsychopharmacology 26, S307.
Yochim, B. P., Mueller, A. E., Kane, K. D., & Kahook, M. Y. (2012). Prevalence of cognitive impairment, depression, and anxiety symptoms among older adults with glaucoma. Journal of Glaucoma, 21(4), 250–254. https://doi.org/10.1097/IJG.0b013e3182071b7e PMID:21336151
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