The effect of aromatherapy using Lavender (Lavandula angustifolia Miller) and Citrus aurantium L. extracts to treat anxiety of patients undergoing laparoscopic cholecystectomy: A randomized clinical trial in Iran

Authors

  • Jamshid Eslami Department of Surgical Technology, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
  • Abed Ebrahimi Department of Surgical Technology, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
  • Ayda Hosseinkhani Department of Traditional Medicine and History of Medicine of Shiraz University of Medical Sciences
  • Zaher Khazaei MSc of Epidemiology, Department of Health and Community Medicine, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran
  • Isan Darvishi Department of Surgical Technology, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran

DOI:

https://doi.org/10.15419/bmrat.v5i3.423

Keywords:

Aromatherapy, Citrus aurantium L., Iran, Lavandula angustifolia Miller, Lavender, Preoperative anxiety, Randomized clinical trial, RCT, State anxiety,, Trait anxiety

Abstract

Introduction: Nowadays, complementary medicine such as aromatherapy has an important application in medicine, particularly in treating anxiety. The objective of the present study was to compare the effects of aromatherapy using lavender (Lavandula angustifolia Miller) and Citrus aurantium L. extracts on the anxiety level of patients undergoing laparoscopic cholecystectomy at Shiraz University of Medical Sciences Training Hospital in Iran.

Methods: This Randomized Clinical Trial (RCT) was carried out in 2017 on a total of 90 patients undergoing laparoscopic cholecystectomy using aromatherapy. The subjects were randomly assigned to 3 groups based on the inclusion and exclusion criteria using sampling methods based on the goals. Two groups received either aromatherapy with Lavandula angustifolia Miller extract, aromatherapy with Citrus aurantium L. extract. The third group (control) received a placebo (odorless oil). The aromatherapy was performed on all subjects for 20 minutes. Patient anxiety was assessed using a Spielberg questionnaire before and after applying the aromatherapy intervention. The data obtained were analyzed by SPSS software via Chi-square test, one-tailed variance analysis, Tukey, t-tests, and Kruskal-Wallis test.

Results: State and trait anxiety decreased for the aromatherapy groups, compared to control group, after applying the aromatherapy (P<0.001); moreover, there was an increased severity of anxiety in the control group (P<0.05). Indeed, the effects of aromatherapy with Lavandula angustifolia Miller and Citrus aurantium L. extracts were observed and confirmed; both extracts significantly decreased the severity of anxiety in the trial groups as compared to the control group (P<0.001). Moreover, the effect of aromatherapy with both of the aforementioned extracts was similar to each other.

Conclusion: There was no significant difference between the lavender (Lavandula angustifolia Miller) and Citrus aurantium L. extracts in aromatherapy; therefore, either extract may be applied and useful in the clinic to alleviate preoperative anxiety. 

Author Biography

  • Abed Ebrahimi, Department of Surgical Technology, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
    Abed.or90@gmail.com

References

Babashahi M, F.S., Mardanian dehkordi L. (2015). Comparison of massage and aromatherapy inhalation on patients’ anxiety before surgery. Journal of Nurse-Midwifery, 13, 284–291.
Bakhsha F, Y.Z., Aryaee M, Jafari SY, Derakhshanpoor F. (2016). Comparison effect of Lavender and Citrus aurantium aroma on anxiety in female students at Golestan University of Medical Sciences. Journal of Basic Research in medical Sciences 6, 4-11.
Chhabra, S. K., Ahmed, Z., Massey, A., Agarwal, S., Vij, V., Agarwal, B., . . . Jenaw, R. K. (2016). Laparoscopic cholecystectomy in a 2 year old male child with choleilithiasis and recurrent right hypochondrial pain: Case report and review of literature. International Journal of Surgery Case Reports, 26, 142–145. https://doi.org/10.1016/j.ijscr.2016.07.038 PMID:27494370
Fayazi, S., Babashahi, M., & Rezaei, M. (2011). The effect of inhalation aromatherapy on anxiety level of the patients in preoperative period. Iranian Journal of Nursing and Midwifery Research, 16(4), 278–283. PMID:23449862
Franco, L., Blanck, T. J., Dugan, K., Kline, R., Shanmugam, G., Galotti, A., . . . Wajda, M. (2016). Both lavender fleur oil and unscented oil aromatherapy reduce preoperative anxiety in breast surgery patients: A randomized trial. Journal of Clinical Anesthesia, 33, 243–249. https://doi.org/10.1016/j.jclinane.2016.02.032 PMID:27555173
Ghardashi, F., SALEH, M.A., Hasanabadi, H., and Setayesh, Y. (2004). Study of the relationship between pre-operative waiting time and anxiety in patients. Journal of Sabzevar University of Medical Sciences, 10(4), 76-84.
Ghardashi, F., Salehe Moghadam, A., Hasanabadi, H., & Setayesh, Y. (2003). Correlation Between Duration of Waiting Befor Surgery and Anxiety of Patients. Sci J Sabzevar Uni Med Sci, 4, 30.
Goes, T. C., Antunes, F. D., Alves, P. B., & Teixeira-Silva, F. (2012). Effect of sweet orange aroma on experimental anxiety in humans. Journal of Alternative and Complementary Medicine (New York, N.Y.), 18(8), 798–804. https://doi.org/10.1089/acm.2011.0551 PMID:22849536
Hur, M. H., Cheong, N., Yun, H., Lee, M., & Song, Y. (2005). [Effects of delivery nursing care using essential oils on delivery stress response, anxiety during labor, and postpartum status anxiety]. Journal of Korean Academy of Nursing, 35(7), 1277–1284. https://doi.org/10.4040/jkan.2005.35.7.1277 PMID:16418554
Kritsidima, M., Newton, T., & Asimakopoulou, K. (2010). The effects of lavender scent on dental patient anxiety levels: A cluster randomised-controlled trial. Community Dentistry and Oral Epidemiology, 38(1), 83–87. https://doi.org/10.1111/j.1600-0528.2009.00511.x PMID:19968674
Lee, M. S., Choi, J., Posadzki, P., & Ernst, E. (2012). Aromatherapy for health care: An overview of systematic reviews. Maturitas, 71(3), 257–260. https://doi.org/10.1016/j.maturitas.2011.12.018 PMID:22285469
Lee, Y.-L., Wu, Y., Tsang, H. W., Leung, A. Y., & Cheung, W. M. (2011). A systematic review on the anxiolytic effects of aromatherapy in people with anxiety symptoms. Journal of Alternative and Complementary Medicine (New York, N.Y.), 17(2), 101–108. https://doi.org/10.1089/acm.2009.0277 PMID:21309711
Leite, M. P., Fassin, J., Jr., Baziloni, E. M., Almeida, R. N., Mattei, R., & Leite, J. R. (2008). Behavioral effects of essential oil of Citrus aurantium L. inhalation in rats. Revista Brasileira de Farmacognosia, 18, 661–666. https://doi.org/10.1590/S0102-695X2008000500003
Muzzarelli, L., Force, M., & Sebold, M. (2006). Aromatherapy and reducing preprocedural anxiety: A controlled prospective study. Gastroenterology Nursing, 29(6), 466–471. https://doi.org/10.1097/00001610-200611000-00005 PMID:17273013
Namazi M, A.A.A.S., Mjab F, Talebi A, Alavimajd H, Jannesari S. (2014). The effect of anxiety on the first notes of orange flower delivery. Journal of Obstetrics Gynecology and Infertility. Journal of Obstetrics Gynecology and Infertility[Persian], 12, 12–19.
Ozgoli, G., Aryamanesh, Z., Mojab, F., & Alavi Majd, H. (2013). A study of inhalation of peppermint aroma on the pain and anxiety of the first stage of labor in nulliparous women: A randomized clinical trial. Qom University of Medical Sciences Journal, 7, 21–27.
Pimenta, F. C. F., Alves, M. F., Pimenta, M. B. F., Melo, S. A. L., de Almeida, A. A., Leite, J. R., . . . de Almeida, R. N. (2016). Anxiolytic Effect of Citrus aurantium L. on Patients with Chronic Myeloid Leukemia. Phytotherapy Research, 30(4), 613–617. https://doi.org/10.1002/ptr.5566 PMID:26787366
Sadati, L., Pazouki, A., Mehdizadeh, A., Shoar, S., Tamannaie, Z., & Chaichian, S. (2013). Effect of preoperative nursing visit on preoperative anxiety and postoperative complications in candidates for laparoscopic cholecystectomy: A randomized clinical trial. Scandinavian Journal of Caring Sciences, 27(4), 994–998. https://doi.org/10.1111/scs.12022 PMID:23350886
Shabanian G, R.M., Shabanian S, homaie S, Shabanian M. (2016). Compare herbal remedy Valerian with diazepam in reducing anxiety before surgery: A randomized, double-blind clinical trial. Journal of Clinical Nursing and Midwifery, 5, 58–66.
Spielberger, C.D., Gorsuch, R.L., and Lushene, R. (1970). State-trait anxiety inventory. Palo Alto (ca: consulting psychologists press).
Steflitsch, W., & Steflitsch, M. (2008). Clinical aromatherapy. The Journal of Men’s Health, 5(1), 74–85. https://doi.org/10.1016/j.jomh.2007.11.001
Yim, V. W., Ng, A. K., Tsang, H. W., & Leung, A. Y. (2009). A review on the effects of aromatherapy for patients with depressive symptoms. Journal of Alternative and Complementary Medicine (New York, N.Y.), 15(2), 187–195. https://doi.org/10.1089/acm.2008.0333 PMID:19216657

Published

2018-03-19

Issue

Section

Original Research

How to Cite

The effect of aromatherapy using Lavender (Lavandula angustifolia Miller) and Citrus aurantium L. extracts to treat anxiety of patients undergoing laparoscopic cholecystectomy: A randomized clinical trial in Iran. (2018). Biomedical Research and Therapy, 5(3), 2096-2110. https://doi.org/10.15419/bmrat.v5i3.423

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