Application of electrochemical aptasensors in detection of cancer biomarkers

Authors

  • Masoud Negahdary Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  • Ali Moradi Department of Biochemistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  • Hossein Heli Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

DOI:

https://doi.org/10.15419/bmrat.v6i7.558

Keywords:

Aptasensor, Electrochemical detection, Aptamer, Cancer, Biomarker

Abstract

Today, the late diagnosis of cancers is a big challenge, and using novel diagnostic techniques will provide essential, faster and more accurate treatments. Unfortunately, existing common and traditional diagnostic methods have not been helpful completely and most cancers are diagnosed too late. Recently, researchers have found new diagnostic methods against cancers by aptasensors; these sensory systems can detect involved biomarkers in various cancers so that the research in this field is continued strictly. Aptasensors can detect cancer markers in small quantities and high selectivity; moreover, other advantages of cancer aptasensors such as optimized time and cost saving can be considered. In addition, the aptasensors have been used in the diagnosis of the effective and related factors in cancer therapy follow-up. Here, the most researches about cancer aptasensors and other involved markers were collected, reviewed and described.

 

Published

2019-07-28

Issue

Section

Review

How to Cite

Application of electrochemical aptasensors in detection of cancer biomarkers. (2019). Biomedical Research and Therapy, 6(7), 3315-3324. https://doi.org/10.15419/bmrat.v6i7.558

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