Toxicity effects of Cubic Cu2O nanoparticles on defecation rate and length in C. Elegans

This article was retracted on 19 February 2022 by author

Authors

  • John Zizzo Department of Biology, University of Miami, Coral Gables, FL; Neuropathology Section, Research & Development, Miami Veterans Affairs Administration Hospital, Miami, FL; Howard Hughes Medical Institute (HHMI) Program, University of Miami, Coral Gables, FL; University of Miami Miller School of Medicine, Miami, FL, United States

DOI:

https://doi.org/10.15419/bmrat.v7i10.639

Keywords:

Neurodegeneration, C. elegans, Nanoparticles, Environmental Pollutants, Metal Oxide Catalyst, SEM

Abstract

This article was retracted by author on 29 Feb 2022

Introduction: The increased presence of radiation and toxins in the atmosphere has given rise to fuel cells and nanoparticle technology with the ability to catalyze reactions at favorable energy levels. The purpose of this experiment was to determine the lasting effects of a synthesized catalyst on a model organism, Caenorhabditis (C.) elegans.

Methods: Copper sulfate was tested alongside copper(I) oxide (i.e. Cu2O) to dissociate the copper composition effects from those of the nanoparticles themselves. The prospect of testing both defecation rate and size differences allowed for C. elegans to be utilized due to their low maintenance costs, mapped neuronal pathways, and short-generation times.

Results: The results indicated significant toxicity effects in wild-type worms as witnessed by the decreases in nematode defecation rate and length by copper sulfate, with similar results in SMF-1 and PCS-1 mutants by Cu2O catalysts in cubic synthesized form.

Conclusion: These outcomes reinforce the known effects of metal oxides on pollutants and highlight the need for further testing with additional variables such as varying pH and temperature.

Published

2020-10-31

Issue

Section

Original Research

How to Cite

Toxicity effects of Cubic Cu2O nanoparticles on defecation rate and length in C. Elegans: This article was retracted on 19 February 2022 by author. (2020). Biomedical Research and Therapy, 7(10), 4045-4051. https://doi.org/10.15419/bmrat.v7i10.639

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