A case of a long course of Osler–Weber–Rendu disease in a 65-year-old patient

Authors

  • Galyna Fadeenko Government Institution L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, 61000, 2a Lyubov Malaya Ave., Kharkov, Ukraine https://orcid.org/0000-0003-0881-6541
  • Alexey Gridnyev Government Institution L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, 61000, 2a Lyubov Malaya Ave., Kharkov, Ukraine https://orcid.org/0000-0003-4716-3520
  • Nataliya Emelyanova Government Institution L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, 61000, 2a Lyubov Malaya Ave., Kharkov, Ukraine https://orcid.org/0000-0001-6089-6206
  • Nataliya Chereliuk Government Institution L.T. Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine, 61000, 2a Lyubov Malaya Ave., Kharkov, Ukraine https://orcid.org/0000-0002-4227-6529

DOI:

https://doi.org/10.15419/bmrat.v8i11.704

Keywords:

autosomal dominant inheritance, hemorrhagic telangiectasias, Osler-Weber-Rendu disease, xerostomia

Abstract

The incidence of Osler–Weber–Rendu disease is low, ranging from 1 detected case per 50,000 to 1 per 100,000 population. The disease is hereditary, with autosomal dominant transmission, caused by pathogenic mutations in genes involved in angiogenesis. The disease has a pronounced clinical picture of multiple telangiectasias of the skin and mucous membranes and manifests as spontaneous bleeding. This scientific article presents a clinical analysis of a 65-year-old patient with a diagnosis of Osler–Weber–Rendu disease. Early identification of the manifestations of this disease and careful observation of the patient give a favorable prognosis of the course and prevent the development of severe complications.

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Published

2021-11-29

Issue

Section

Case report

How to Cite

A case of a long course of Osler–Weber–Rendu disease in a 65-year-old patient. (2021). Biomedical Research and Therapy, 8(11), 4682-4688. https://doi.org/10.15419/bmrat.v8i11.704

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