Authors
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Muhammad Abu Talha Safdar Hashmi
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Muhammad Babar Khawar
Applied Molecular Biology & Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan
https://orcid.org/0000-0002-1812-0591
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Rimsha Naseem
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Ali Afzal
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
https://orcid.org/0000-0003-3679-1257
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Nayab Shahid
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Muddasir Hassan Abbasi
Cell and Molecular Biology Lab, Institute of Zoology, University of the Punjab, Lahore, Pakistan
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Nadeem Sheikh
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Nimra Afzal
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Maryam Mukhtar
Department of Structural and Cell Biology, Tulane University, USA
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Sara Shahzaman
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Syeda Eisha Hamid
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Ume Habiba
Department of Zoology, University of Education, Lahore, Pakistan
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Adil Farooq
Department of Zoology, University of Okara, Punjab, Pakistan
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Muhammad Ahsan Ashraf
Department of Zoology, University of Education, Lahore, Pakistan
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Rabia Mehmood
Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan
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Muhammad Idnan
Department of wildlife & Ecology, University of Okara, Okara, Pakistan
Keywords:
Proteasome Inhibitors, Polyamines, Bacteriocins, Flavonoids, Central Nervous System Neoplasms, Inflammation
Abstract
Microbes release important metabolites that regulate various physiological activities inside and outside of organisms. The human gastrointestinal tract is a reservoir of microbes that play important regulatory roles in modulating the immune system and numerous other physiological functions. Thus, there is substantial interest in these microbial products and their clinical significance. These microbial metabolites have shown promise as therapies for cancer, inflammation, neurological disorders, and many other diseases. Here, we discuss microbial metabolites with substantial therapeutic potential, including proteasome inhibitors, therapeutic enzymes, bacteriocins, polyamines, and flavonoids.
License
Copyright The Author(s) 2017. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
