Antithrombin deficiency with portal vein and superior mesenteric vein thrombosis—a case report
DOI:
https://doi.org/10.15419/bmrat.v11i2.862Keywords:
antithrombin deficiency, hypercoagulable, venous thromboembolismAbstract
Introduction: A deficiency in antithrombin (AT) can be hereditary or acquired. It is characterized by an AT activity level that is less than 80% of normal or the lower limit of the reference range on a regular basis. In some cases, AT deficiency has been linked to an increased risk of thromboembolism.
Case presentation: We present the case of a 56-year-old Malay man with long-segment thrombosis of the portal vein and superior mesenteric vein with small bowel ischemia. He was diagnosed with AT deficiency following an extensive hematological and thrombophilia workup supported by a strong familial history of venous thromboembolism (VTE) affecting his brothers and sister.
Conclusion: Inherited AT deficiency must be considered when spontaneous VTE occurs in young patients with unusual localizations, such as mesenteric veins and portal veins.
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Copyright The Author(s) 2017. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
