Intensification of Metformin treatment in diabetic patients with Insulin versus Sulfonylureas
DOI:
https://doi.org/10.15419/bmrat.v4i06.177Keywords:
Treatment, Diabetic Patients, Insulin, Sulfonylureas, Metformin, BiologyAbstract
Diabetes is one of the most common chronic diseases, so that the number of diabetics was 221 million worldwide in 2010. Diabetes has no decisive cure and can lead to fatal complications. This disease is the most common cause of amputation, blindness and chronic renal failure and one of the most important risk factors for coronary heart diseases (Masoudi et al., 2004). The global incidence of diabetes is increasing due to the increased obesity and decreased physical activity (Bidarpour et al., 2003). Non-insulin dependent or type 2 diabetes is now an epidemic in the United States; and it had the prevalence of 7 percent in adults over 30 years in 2000 (Hillier and Pedula, 2001).
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References
Fenton, J.J., Von Korff, M., Lin, E.H., Ciechanowski, P., and Young, B.A. (2006). Quality of preventive care for diabetes: effects of visit frequency and competing demands. The Annals of Family Medicine 4, 32-39.
Harrison, L.B., Adams-Huet, B., Raskin, P., and Lingvay, I. (2012). beta-cell function preservation after 3.5 years of intensive diabetes therapy. Diabetes Care 35, 1406-1412.
Hillier, T.A., and Pedula, K.L. (2001). Characteristics of an adult population with newly diagnosed type 2 diabetes. Diabetes care 24, 1522-1527.
Holden, S.E., Poole, C.D., Morgan, C.L., and Currie, C.J. (2011). Evaluation of the incremental cost to the National Health Service of prescribing analogue insulin. BMJ open 1, e000258.
Inzucchi, S.E., Bergenstal, R.M., Buse, J.B., Diamant, M., Ferrannini, E., Nauck, M., Peters, A.L., Tsapas, A., Wender, R., and Matthews, D.R. (2012). Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 35, 1364-1379.
Masoudi, A.N., Ghofranipour, F., Ahmadi, F., Babaei, G.H., and Rajab, A. (2004). Evaluation of effectiveness of community based interventions on controlling diabetes mellitus in Tehran, 1382. Iranian Journal of Diabetes And Lipid Disorders, 85-93.
Pringle, M., Stewart-Evans, C., Coupland, C., Williams, I., Allison, S., and Sterland, J. (1993). Influences on control in diabetes mellitus: patient, doctor, practice, or delivery of care? Bmj 306, 630-634.
Roumie, C.L., Greevy, R.A., Grijalva, C.G., Hung, A.M., Liu, X., Murff, H.J., Elasy, T.A., and Griffin, M.R. (2014). Association between intensification of metformin treatment with insulin vs sulfonylureas and cardiovascular events and all-cause mortality among patients with diabetes. Jama 311, 2288-2296.
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Copyright The Author(s) 2017. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
