Authors
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Karina Karina
Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia; HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia; Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia; Pusat Kajian Stem Cell, Universitas Pembangunan Nasional Veteran Jakarta, Indonesia
https://orcid.org/0000-0003-3159-3892
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Louis Martin Christoffel
Koja Regional Public Hospital, Jl. Deli No. 4, Jakarta, Indonesia
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Rita Novariani
Koja Regional Public Hospital, Jl. Deli No. 4, Jakarta, Indonesia
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Imam Rosadi
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia
https://orcid.org/0000-0001-6988-3495
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Iis Rosliana
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Siti Rosidah
Koja Regional Public Hospital, Jl. Deli No. 4, Jakarta, Indonesia
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Siti Sobariah
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Novy Fatkhurohman
Koja Regional Public Hospital, Jl. Deli No. 4, Jakarta, Indonesia
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Nurlaela Puspitaningrum
Koja Regional Public Hospital, Jl. Deli No. 4, Jakarta, Indonesia
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Yuli Hertati
Koja Regional Public Hospital, Jl. Deli No. 4, Jakarta, Indonesia
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Irsyah Afini
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Difky Ernanda
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Tias Widyastuti
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Sulaeha AD
Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Alfida Zakiyah
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Noor Aini
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia
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Hubert Andrew
HayandraLab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 6, Jakarta, Indonesia
https://orcid.org/0000-0002-8881-9787
Keywords:
Autologous activated platelet-rich plasma, Coronavirus disease 2019, Disseminated intravascular coagulation, Inflammation, Nosocomial infection
Abstract
In most people, COVID-19 presents as a mild disease. However, in many people, especially those with comorbidities, profound inflammation manifesting as a cytokine storm may lead to acute respiratory distress syndrome and multi-organ failure. This novel study reports two severe COVID-19 patients from Koja Regional Hospital: a male aged 52 and a female aged 65. Both patients had poor prognoses based on prognostic biomarkers, disseminated intravascular coagulation, nosocomial infections, and were reintubated more than once. Both patients were treated with adjunct autologous activated platelet-rich plasma — a safe and promising therapy — and were ultimately discharged. Thus, this study reports the potential of autologous activated platelet-rich plasma as supportive therapy for severe COVID-19 patients.
License
Copyright The Author(s) 2017. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
How to Cite
Case Report on Adjunct Intravenous Autologous Activated Platelet-Rich Plasma Therapy in Severely Ill COVID-19 Patients. (2021).
Biomedical Research and Therapy,
8(10), 4614-4619.
https://doi.org/10.15419/bmrat.v8i10.697
